SUNNYVALE, Calif., February 25, 2010 - Symyx Technologies, Inc. (Nasdaq: SMMX) today announced that Isy Goldwasser, the Company's Chief Executive Officer, is scheduled to present at the America's Growth Capital Annual West Coast Emerging Growth Conference in San Francisco on March 2 at 11:10 a.m. Pacific Time.

A live webcast of the presentation may be accessed over the internet at http://investor.symyx.com/events.cfm. The webcast audio and slides will be available for a period of thirty days.

Symyx Technologies, Inc. (NASDAQ: SMMX) helps R&D-based companies in life sciences, chemicals, energy, and consumer and industrial products achieve breakthroughs in innovation, productivity, and return on investment. Symyx software and scientific databases power laboratories with the information that generates insight, enhances collaboration, and drives productivity. Products include a market-leading electronic laboratory notebook, decision support software, and chemical informatics and sourcing databases. Symyx high-productivity research (HPR) products and services help scientists exploit the value of microscale, high-throughput experimentation, which was pioneered by Symyx. Using these technologies, a single scientist can rapidly explore a broad experimental space using small amounts of material. As a result, laboratories can develop comprehensive data sets and directional information in just a few days. Information about Symyx, including reports and other information filed by Symyx with the Securities and Exchange Commission, is available at www.symyx.com.

Symyx is a registered trademark of Symyx Technologies, Inc. All rights reserved.