Metabolic fates of foreign compounds introduced to living systems are stored as searchable schemes of biotransformations leading from the parent compound to isolated metabolites.

Symyx Metabolite: the world’s most comprehensive collection of xenobiotic compounds and biotransformations (primarily medicinal drugs).

The database indexes path and scheme information and experimental data from in vivo and in vitro studies compiled from primary literature, conference proceedings, and New Drug Applications.

Isentris offers a graphical interface for searching and displaying metabolic schemes stored in either the Metabolite Database or corporate databases. Explore metabolic outcomes of known compounds studied in living systems (human, animal, tissue, tissue extracts, and cellular studies). Discover shared metabolic pathways of structurally related systems.

Symyx Metabolite can be used in conjunction with Symyx Toxicity. A single click enables structure browsing in either database to transfer and view relevant toxicity and biotransformation data.