Symyx provides contract research and manufacturing services for pharmaceutical companies seeking to outsource preformulation, formulation and process development research studies for chemical or biologic drug development.
Explore a greater experimental space with micro–scale, parallel experimentation that delivers results in days – not weeks or months. Decide which drug candidates move forward based on comprehensive data with GMP fill/finish services for biopharmaceuticals and small molecule parenteral clinical supply.
Symyx Research Services delivers liquid or lyophilized drug product packaged under GMP conditions, while maintaining the integrity of drug substances to meet demanding preclinical and phase I and II clinical trial schedules.
Symyx provides:
Preformulation
- API solubility and early liquid formulation stability
- Polymorph screening, optimal counterions for salt selection, and co–crystallization development
Formulation
- Accelerated stress testing and liquid formulation stability
- Excipients and drug substance compatibility
Process Development
- Array based process route selection and process development
- Expertise in chiral transformations, catalytic reactions, and general organic synthesis
Preformulation
- Accelerated stress testing and degradant identification
- Physical and biologic characterization and formulation development
Formulation
- Formulation optimization and long–term stability studies
- Lyophilized or liquid formulation
Analytical Development
- Analytical method development including HPLC, MS, and structural analysis
Preclinical, Phase I and Phase II supply capable of:
- Manual and automated aseptic filling and capping
- Sterile lyophilized formulation production and lyophilization cycle development services
- Final product testing services